Abstract
Cardiomegaly in rats was induced by experimental aortic stenosis caused by slowly constricting rings placed on the abdominal aorta. The capacity of the terminal vessels per gram of left ventricle was significantly lower in these animals as compared to normal rats. Chronic treatment with heart extract prevented this decrease without influencing heart growth. Tissue hematocrit in hypertrophied hearts due to aortic constriction was also significantly lower than in the normal heart. The results indicate that capillary capacity in cardiomegaly depends on the age of animals in which pathological growth of the heart occurs. On the other hand, the values of hematocrit in the coronary vessels in the same situation are determined by the type of mechanism which induces the pathological growth.
Publisher
Canadian Science Publishing
Subject
Physiology (medical),Pharmacology,General Medicine,Physiology
Cited by
24 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献