Abstract
An interpretation is provided for the phenomenon of macromolecule inhibition of hemoglobin release from hemolyzing erythrocytes. High concentrations of macromolecules, which are extensively hydrated, remove solvent volume accessible to the diffusing hemoglobin, thus retarding the diffusion. This explanation considerably alters previous interpretations of the mechanism of immune lysis of cells.
Publisher
Canadian Science Publishing
Subject
Physiology (medical),Pharmacology,General Medicine,Physiology
Cited by
14 articles.
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