Short-term remote ischemic preconditioning is not associated with improved blood pressure and exercise capacity in young adults

Author:

Banks Laura1,Wells Greg D.23,Clarizia Nadia A.1,Jean-St-Michel Emilie1,McKillop Adam L.1,Redington Andrew N.14,McCrindle Brian W.14

Affiliation:

1. Labatt Family Heart Centre, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.

2. Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada.

3. Physiology and Experimental Medicine, the Hospital for Sick Children, Toronto, ON, Canada.

4. Department of Pediatrics, University of Toronto, Toronto, ON, Canada.

Abstract

We sought to determine whether a 9-day remote ischemic preconditioning (IPC) causes improvements in exercise performance, energetics, and blood pressure. Ten participants (mean age 24 ± 4 years) had no changes in aerobic capacity (preintervention: 38 ± 10 mL/(kg·min)–1 vs. postintervention: 38 ± 10 mL/(kg·min)–1), blood pressure (preintervention: 112 ± 7/66 ± 6 mm Hg vs. postintervention: 112 ± 10/62 ± 5 mm Hg), cardiac phosphocreatinine-to-adenosine–triphosphate ratio (preintervention: 2.1 ± 0.5 vs. postintervention: 2.3 ± 0.4), and postexercise skeletal muscle phosphocreatine recovery (preintervention: 34 ± 11 s vs. postintervention: 31 ± 11 s). Short-term remote IPC may be ineffective in improving these outcomes.

Publisher

Canadian Science Publishing

Subject

Physiology (medical),Nutrition and Dietetics,Physiology,General Medicine,Endocrinology, Diabetes and Metabolism

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