Weight loss efficacy of alternate day fasting versus daily calorie restriction in subjects with subclinical hypothyroidism: a secondary analysis

Author:

Akasheh Rand T.12,Kroeger Cynthia M.13,Trepanowski John F.1,Gabel Kelsey1,Hoddy Kristin K.1,Kalam Faiza1,Cienfuegos Sofia1,Varady Krista A.1

Affiliation:

1. Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, USA.

2. Department of Nutrition and Dietetics, American University of Madaba, Madaba, Jordan.

3. Charles Perkins Center, The University of Sydney, Sydney, NSW, Australia.

Abstract

This study compared the weight loss efficacy of alternate-day fasting (ADF) versus daily calorie restriction (CR) in adults with subclinical hypothyroidism. After 6 months, body weight decreased (P < 0.001) similarly by ADF (–7% ± 1%) and CR (–8% ± 2%). Insulin resistance decreased (P < 0.05) more by ADF versus CR. Free thyroxin and thyroid-stimulating hormone remained unchanged. Thus, ADF and CR produce similar weight loss in this population, without affecting thyroid hormone levels. Novelty Intermittent fasting and daily restriction produce similar reductions in body weight in subjects with subclinical hypothyroidism.

Publisher

Canadian Science Publishing

Subject

Physiology (medical),Nutrition and Dietetics,Physiology,General Medicine,Endocrinology, Diabetes and Metabolism

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