Affiliation:
1. Natural Products Laboratory, School of Pharmacy, Sungkyunkwan University, 300 Chonchon-dong, Jangan-ku, Suwon 440-746, Korea.
Abstract
Bistorta manshuriensis is a well-known Korean medicinal plant traditionally used to treat diarrhea. Phytochemical investigation of the aerial parts of B. manshuriensis led to the isolation of two new feruloyl sucrose derivatives, bistoroside A (1) and bistoroside B (2), together with three known compounds, helonioside A (3), helonioside B (4), and smilaside L (5). The structures of the new compounds were elucidated as (3,6-di-O-Z-feruloyl)-β-D-fructofuranosyl-(1→2)-α-D-glucopyranoside (1) and (3,6-di-O-Z-feruloyl)-β-D-fructofuranosyl-(1→2)-(6′-O-acetyl)-α-D-glucopyranoside (2) on the basis of extensive analysis of 1D and 2D NMR (HMQC and HMBC), HR-FAB-MS, and chemical evidence.
Publisher
Canadian Science Publishing
Subject
Organic Chemistry,General Chemistry,Catalysis
Reference16 articles.
1. Natural Products Research Institute. Medicinal Plants in the Republic of Korea; World Health Organization: Seoul, 1998; p. 53.
2. Editorial Committee of the Pharmacopoeia of People’s Republic of China. The Pharmacopoeia of People’s Republic of China, Part 1; Chemical Industry Press: Beijing, 2000; p. 239.
3. Anti-inflammatory Activity of Polygonum bistorta, Guaiacum officinale and Hamamelis virginiana in Rats
4. The Anti-Inflammatory Compounds ofPolygonum bistorta: Isolation and Characterisation
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