Abstract
The enzymatic transfer of deoxyribose from a purine or a pyrimidine deoxyriboside to a carbon-14 labeled purine or pyrimidine base affords an efficient means of preparing labeled deoxyribonucleosides. Deoxyadenosine-8-C14, deoxyguanosine-8-C14, deoxycytidine-2-C14, and thymidine-2-C14, with the natural β-configuration, were prepared in good yields and isolated in radiochemically pure form by large-scale paper chromatography.
Publisher
Canadian Science Publishing
Subject
Organic Chemistry,General Chemistry,Catalysis
Cited by
9 articles.
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