DNA from Eukaryotic Cells Contains Unusually Long Pyrimidine Sequences

Author:

Birnboim H. C.,Straus N. A.

Abstract

Analysis of DNA samples from several different organisms revealed the presence of unexpectedly long pyrimidine tracts (polypyrimidines), ranging in size from about 25 to 200 nucleotides in length. This fraction of the DNA accounted for 0.07–0.8% of the total thymidine residues. Pyrimidine clusters of this length and amount would not be expected on a random basis, suggesting they may have been conserved during evolution because they are required for a specialized function(s).

Publisher

Canadian Science Publishing

Subject

General Medicine

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