THE EFFECT OF INTRAVASCULAR PRESSURE CHANGES ON BLOOD FLOW

Abstract

The sudden intra-arterial injection of saline, Locke's solution, or blood, at different speeds into the arteries of dogs, caused an increase in blood flow at the site of injection and distal to it. The decrease in the vascular resistance, produced by this stretching, was more marked in the femoral than in the carotid artery of the dog. Intact vascular innervation is not required to obtain this effect. The results suggest that the vascular response to stretching, used in these experiments, would not be simply a passive one. The results do not support the myogenic theory of Bayliss and of Folkow.