Author:
Tsui P. T.,Kelly K. A.,Ponpipom M. M.,Strahilevitz M.,Sehon A. H.
Abstract
The syntheses of four distinct derivatives of Δ9-tetrahydrocannabinol (Δ9-THC), intended for subsequent coupling to proteins and for use as hapten–protein conjugates for the production of anti-THC antibodies, are described. Three of these THC derivatives were coupled to proteins with the aid of the water-soluble carbodiimide, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride, and the fourth in the form of THC-isocyanate was conjugated directly to proteins.
Publisher
Canadian Science Publishing
Cited by
12 articles.
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