Author:
Leong M. M. L.,Lin C. C.,Ruth R. F.
Abstract
Pig – mouse somatic cell hybrids were obtained by fusing pig lymphocytes with mouse cells of the RAG (HPTR) line using polyethylene glycol. The expression of pig superoxide dismutase (SOD-1) activity in 11 hybrid clones as well as in the parental cells was investigated. Seven hybrid clones positive for the expression of pig SOD-1 displayed the corresponding parental RAG and pig bands of SOD-1 plus a heteropolymeric band of intermediate elcctrophoretic mobility. The positive and negative expression of pig SOD-1 was concordant with the retention and loss of pig chromosome No. 9, suggesting that the gene for pig SOD-1 is located on the chromosome No. 9 of the domestic pig.
Publisher
Canadian Science Publishing
Subject
Cell Biology,Plant Science,Genetics
Cited by
18 articles.
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