Author:
Bozzola J. J.,Mehta R. J.,Nisbet L. J.,Valenta J. R.
Abstract
Transmission (TEM) and scanning electron microscopy (SEM) of Candida albicans cultures treated with the cell wall active antibiotics aculeacin A and papulacandin B (10 μg/mL) revealed highly distorted, wrinkled, and collapsed cells. Dividing cells failed to separate properly and aggregates of enlarged and elongated forms were often seen. TEM sections revealed thick and layered cell walls in the treated cultures and bud cross walls failed to segregate completely. Approximately 20% of the cells demonstrated complete cell necrosis accompanied with cytoplasmic deterioration, layered and distorted walls, and improperly formed buds and scars.
Publisher
Canadian Science Publishing
Subject
Genetics,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Immunology,Microbiology
Cited by
27 articles.
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