THE ALKALOIDS OF FUMARIACEOUS PLANTS: XIX. CORYDALIS OPHIOCARPA HOOK. f. ET THOMS

Abstract

Nine alkaloids have been isolated from Corydalis ophiocarpa only one of which, ophiocarpine, C20H21O5N (F39), is definitely characterized as new. It is a hydroxy-canadine in which the hydroxy group probably occurs in position 13. A second alkaloid, which may be new, is referred to as alkaloid F40. Berberine, its tetrahydro-derivative, namely l-canadine, and l-corypalmine constitute the remaining protoberberine alkaloids that were found. The presence of l-adlumine was established. This is the third plant from which it has been isolated. In addition, protopine, α-allocryptopine and cryptocavine, all of which contain the ten-membered ring characteristic of the first, were isolated.