β-Ketoalkylthioacrylic acid derivatives as precursors of thiophenes, thiazolines, and thienopyrimidines-Reference-Cited by-同舟云学术

β-Ketoalkylthioacrylic acid derivatives as precursors of thiophenes, thiazolines, and thienopyrimidines

Published:1970-09-01 Issue:17 Volume:48 Page:2709-2717
ISSN:0008-4042
Container-title:Canadian Journal of Chemistry
language:en
Short-container-title:Can. J. Chem.

Author:

Laliberté Réal,Médawar Georges

Abstract

Reactions of sodium salts of substituted 3-amino-2-cyano-3-thioacrylic esters and amides with α-halomethylketones were studied. Conditions were found which led to the synthesis of either 5-acyl-2,4-diaminothiophene-3-carboxylic esters and amides or thiazoline-Δ2α-acetic esters and amides. Some thiophene-3-carboxamides were also transformed into thienopyrimidines upon acetylation.

Publisher

Canadian Science Publishing

Subject

Organic Chemistry,General Chemistry,Catalysis

Link

http://www.nrcresearchpress.com/doi/pdf/10.1139/v70-457

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