Author:
Mojtahedi Mohammad M,Abaee M Saeed,Abbasi Hassan
Abstract
A three-component, efficient, and facile procedure has been developed for the synthesis of α-aminonitriles from aldehydes, amines, and trimethylsilyl cyanide using a catalytic amount of magnesium bromide ethyl etherate in the absence of solvent. Rapid formation of products is observed at room temperature in a one-pot procedure under very mild conditions giving excellent yields of the title compounds.Key words: catalyzed Strecker's reaction, α-aminonitriles, magnesium bromide, solvent-free.
Publisher
Canadian Science Publishing
Subject
Organic Chemistry,General Chemistry,Catalysis
Cited by
33 articles.
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