Author:
YoungLai E. V.,Edwards R. G.,Steptoe P. C.
Abstract
Follicular contents were aspirated during laparoscopy just before ovulation from eight follicles from patients pretreated with human menopausal gonadotropin and human chorionic gonadotropin. The aspirates from each follicle were incubated for 1 h in a modified Tyrode B medium containing radioactive pregnenolone and progesterone in order to determine the relative efficiency of the 3β-hydroxysteroid dehydrogenase and 17α-hydroxylase systems. Labelled 17α-hydroxyprogesterone was not isolated but the conversion of pregnenolone to progesterone ranged from 9.9% to 45.4% of the recovered radioactivity.
Publisher
Canadian Science Publishing
Cited by
7 articles.
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