Author:
Ketcheson Barbara G.,Taurins Alfred
Abstract
Reduction of methyl 3β-acetoxy-6-oximinodinorcholanate using sodium in n-propyl alcohol, and acetylation, gave 6α-acetamido-3β-acetoxydinorcholanic acid; treatment with lithium aluminum hydride in tetrahydrofuran provided 3β,22ξ-dihydroxydinorcholan-6-one. High-pressure hydrogenation of methyl 3β-acetoxy-6-nitro-5-dinorcholenate, using palladium black as catalyst in acetic acid medium, afforded methyl 6ξ-acetamido-3β-acetoxy-5α-dinorcholanate. Under identical conditions, catalytic hydrogenation of 3β-acetoxy-6-nitro-5-cholestene resulted in the formation of 6β-acetamido-3β-acetoxy-5α-cholestane and 6ξ-acetamido-3β-acetoxy-5β-cholestane.
Publisher
Canadian Science Publishing
Subject
Organic Chemistry,General Chemistry,Catalysis
Cited by
11 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献