Author:
Hawkins W. W.,Leonard Verna G.
Abstract
When laminarin sulphate was injected intravenously into dogs it acted as an antithrombic agent. As such it was about one-third as potent as heparin. It also showed anticoagulant activity when administered subcutaneously and intramuscularly to the dog.After the intravenous administration of a moderate amount of laminarin sulphate or of heparin to the dog, considerable anticoagulant material passed into the urine. When large oral doses were given to the rat, absorption from the intestine was very small, and much of the material passed into the faeces.When it was given intravenously, laminarin sulphate acted like heparin in clearing alimentary lipaemia in the dog and the rat.
Publisher
Canadian Science Publishing
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献