An Approach to Stereochemical Analysis by Ion Cyclotron Resonance. Distinguishing exo- and endo-Norborneol

Abstract

The ion cyclotron resonance spectra of mixtures of biacetyl and exo- or endo-norborneol show differences in the acetylation of the alcohol by the m/e 129 ion formed from biacetyl. The differences may be interpreted as a difference by a factor of four in rates of acetylation; a steric effect is proposed as the cause of the difference.