Functional characterization ofKlHEM13, a hypoxic gene ofKluyveromyces lactis-Reference-Cited by-同舟云学术

Functional characterization ofKlHEM13, a hypoxic gene ofKluyveromyces lactis

Published:2005-03-01 Issue:3 Volume:51 Page:241-249
ISSN:0008-4166
Container-title:Canadian Journal of Microbiology
language:en
Short-container-title:Can. J. Microbiol.

Author:

Blanco Moisés,Becerra Manuel,González-Siso M Isabel,Cerdán M Esperanza

Abstract

The KlHEM13 gene of Kluyveromyces lactis encoding the coproporphyrinogen oxidase (EC 1.3.3.3), an oxygen-requiring enzyme that catalyzes the sixth step of heme biosynthesis, was cloned and functionally characterized. The coding and upstream regions of KlHEM13 were analyzed and the putative cis regulatory elements were discussed in relation to the mechanisms of regulation of this hypoxic gene in K. lactis.Key words: coproporphyrinogen oxidase (CPO), HEM13, hypoxic genes, Kluyveromyces lactis.

Publisher

Canadian Science Publishing

Subject

Genetics,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Immunology,Microbiology

Link

http://www.nrcresearchpress.com/doi/pdf/10.1139/w04-133

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