Author:
Benderly Abraham,Fuller George B.,Knaus Edward E.,Redda Kinfe
Abstract
The reaction of 2-epoxyethylenepyridine 1-oxide (4), obtained by m-chloroperbenzoic acid oxidation of 2-vinylpyridine (2), with nitrogen, oxygen, and sulfur nucleophiles has been investigated. Reaction of 4 with cyclic or acyclic amines affords pyridylethanolamine 1-oxides 8 which on reductive deoxygenation using palladium-on-charcoal and hydrogen give rise to pyridylethanolamines 9. Similar reactions with sodium ethoxide and sodium thiophenol yield the respective ethyleneglycol 8f and thioethanol 8g derivatives.
Publisher
Canadian Science Publishing
Subject
Organic Chemistry,General Chemistry,Catalysis
Cited by
6 articles.
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