Author:
Engel Ch. R.,Just G.,Buttery R.
Abstract
An improved synthesis of 11-dehydro-17α-methylprogesterone, previously synthesized by this group, has been devised. The new hormone analogue has the same luteoid activity as 17α-methylprogesterone; in this case, the 11,12-unsaturation has no potentiating effect on the progestational activity. Some stereochemical aspects of the Faworsky rearrangement of 17α-halo-20-keto steroids are discussed in a preliminary fashion.
Publisher
Canadian Science Publishing
Subject
Organic Chemistry,General Chemistry,Catalysis
Cited by
10 articles.
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