Isomerization of 4-amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones-Reference-Cited by-同舟云学术

Isomerization of 4-amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones

Published:2006-08-01 Issue:8 Volume:84 Page:1074-1078
ISSN:0008-4042
Container-title:Canadian Journal of Chemistry
language:en
Short-container-title:Can. J. Chem.

Author:

Seebacher Werner,Saf Robert,Brun Reto,Kaiser Marcel,Weis Robert

Abstract

Under strongly basic conditions (6SR,7SR)-4-amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones isomerized regioselectively in position 6 giving their (6RS,7SR) analogues. The structure of the new products was established with the aid of NMR experiments.Key words: aminobicyclo[2.2.2]octanones, isomerization, structure elucidation.

Publisher

Canadian Science Publishing

Subject

Organic Chemistry,General Chemistry,Catalysis

Link

http://www.nrcresearchpress.com/doi/pdf/10.1139/v06-135

Reference11 articles.

1. One-pot synthesis of 4-aminobicyclo[2.2.2]octan-2-ones

2. 4-Aminobicyclo[2.2.2]octanone Derivatives with Antiprotozoal Activities

3. New 4-aminobicyclo[2.2.2]octane derivatives and their activities against Plasmodium falciparum and Trypanosoma b. rhodesiense

4. Antiprotozoal activities of new bicyclo[2.2.2]octan-2-imines and esters of bicyclo[2.2.2]octan-2-ols

5. Synthesis and evaluation of the antitrypanosomal and antiplasmodial activities of new 4-aminobicyclo[2.2.2]octane derivatives

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. New Bicyclic Amines: Synthesis and SARs of their Action Against the Causative Organisms of Malaria and Sleeping Sickness;Current Medicinal Chemistry;2009-04-01

2. SARs of the antiprotozoal action of 6,7-diaryl-bicyclo[2.2.2]octan-2-ols;Monatshefte für Chemie - Chemical Monthly;2008-10-31

3. Antiprotozoal Activities of Epimeric Aminobicycles;Monatshefte für Chemie - Chemical Monthly;2007-05-11

4. Isomerization of 4-Amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones.;ChemInform;2007-04-10