Studies in terpenoids. IV. Synthetic studies in juvabiones and analogues. Conversion of ar- (+)-turmerone to ar- (+)-juvabione

Abstract

Synthetic work leading to the preparation of todomatuic acids (2a), juvabiones (2b), and ar-(±)-juvabione (8d) and the successful conversion of ar-(+)-turmerone (9) to ar-(+)-juvabione (3b) is presented. The synthetic compounds 2b and 3b exhibit juvenile hormone activity.