Affiliation:
1. Département de Physiologie, Faculté de Médecine, Université de Montréal, Montreal, Quebec
Abstract
The treatment of rats with an antihistaminic, or a long pretreatment with a histamine depletor, inhibits the "anaphylactoid" inflammation, and inhibits the sensitizing effect of insulin on this inflammation. However, the systemic administration of histamine, serotonin, and heparin does not restore the inhibited "anaphylactoid" inflammation, and does not restore the sensitizing effect of insulin. The three substances administered systemically are also unable to imitate, in normal rats, the sensitizing effect of insulin.
Publisher
Canadian Science Publishing
Cited by
2 articles.
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1. Reactivity of Rat and Man to Egg-White;Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques;1969
2. A Pharmacological Approach to Allergy;Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des Recherches Pharmaceutiques;1961