cis- and trans-Platinum compounds of substituted pyrimidines and their products from thiourea in Kurnakov's reaction

Abstract

cis- and trans-[Pt(pm)2X2] (where pm = 2-aminopyrimidine, 4-phenylpyrimidine, 4-methyl-pyrimidine and X = Cl, Br) were prepared and characterized. The cis compounds were isolated from the reaction of K2PtCl4 and pm in water, while trans-[Pt(pm)2X2] was obtained by isomerization of cis-[Pt(pm)2X2] in dimethylsulfoxide. The cis- and trans-isomers react with thiourea (tu) to give different products (Kurnakov's test).[Formula: see text]The complexes trans-[Pt(pm)2(tu)2]X2 were isolated and characterized.