Codon indices as a predictor of gene functionality in aFrankiaoperon

Abstract

The mutational response index and measurements of codon bias were determined in eight potential open reading frames in a Frankia operon that encodes genes for nitrogen fixation. The functionality of the different open reading frames is assessed in light of these results and compared with previously published results, as is the applicability of these techniques to the assessment of translational function of putative open reading frames.Key words: Frankia, codon usage, codon bias, open reading frames, mutation pressure.