Pancreatic-Like Ribonuclease Activity in the Ascites Fluid of the Novikoff and Ehrlich Tumors
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Published:1972-07-01
Issue:7
Volume:50
Page:843-845
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ISSN:0008-4018
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Container-title:Canadian Journal of Biochemistry
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language:en
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Short-container-title:Can. J. Biochem.
Author:
Miron Michel,Morais Réjean
Abstract
The ascitic fluid of Novikoff and Ehrlich tumors contains a pancreatic-like ribonuclease. The enzyme catalyzes the hydrolysis of natural RNA and that of the synthetic pyrimidine (poly U, poly C) but not (poly A, poly G) or slightly (poly I) purine polymers. The synthetic duplex molecules poly I: poly C and poly A: poly U are rather resistant to hydrolysis.
Publisher
Canadian Science Publishing