Use of aldolases in the synthesis of non-carbohydrate natural products. Stereoselective synthesis of aspicilin C-3—C-9 fragment

Abstract

The C-3—C-9 main fragment of aspicilin was prepared via a fructose 1,6-diphosphate aldolase reaction. The same fragment was also synthesized by chemical transformation starting from D-arabinose. Key words: aldolase, aspicilin, arabinose, synthesis.