PERCENTAGE OF ALPHA-LIPOPROTEINS, TOTAL CHOLESTEROL, AND ATHEROSCLEROSIS

Abstract

A relatively rapid procedure for the routine estimation of lipoproteins in prestained human sera by zone electrophoresis in paper was described. This technique was employed for the study of the percentage of alpha-lipoproteins in sera of healthy and coronary male subjects of various ages. The mean proportion of alpha-lipoproteins in healthy males (100) was observed to be about 24% in subjects at the age of 20–29 and 16% at the age of 30–59. In the coronary group (105) the mean percentage of alpha-lipoproteins was lower than 13% irrespective of age. From this study, the diagnostic value of alpha-lipoproteins percentage to characterize a coronary patient appeared to be superior to total cholesterol concentrations.