IRRADIATION OF DIPHOSPHOPYRIDINE NUCLEOTIDE IN DILUTE AQUEOUS SOLUTIONS

Author:

Myers D. K.1

Affiliation:

1. Biology Branch, Atomic Energy of Canada Limited, Chalk River, Ontario

Abstract

In extension of previous in vivo experiments, the effects of X irradiation on DPN were studied in vitro. No correlation between the effects on the ultraviolet absorption spectrum and on the coenzyme function of DPN was evident after irradiation at different pH values. However, the loss of coenzyme function could be correlated with the destruction of ribose and of riboside linkages. Catalase did not provide greater protection than did other proteins. It was concluded that the observed loss of DPN from irradiated cells is not due to the radiosensitivity of the DPN molecule itself.

Publisher

Canadian Science Publishing

Subject

General Medicine

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. EFFECT OF IONIZING RADIATION ON THE PYRIDINE NUCLEOTIDES OF THYMOCYTES;Canadian Journal of Biochemistry and Physiology;1963-06-01

2. EFFECT OF IONIZING RADIATION ON THE PYRIDINE NUCLEOTIDES OF THYMOCYTES;Canadian Journal of Biochemistry and Physiology;1963-01-01

3. X-IRRADIATION OF RIBOSE AND DEOXYRIBOSE DERIVATIVES;Canadian Journal of Biochemistry and Physiology;1962-11-01

4. EFFECTS OF X-RADIATION AND OF METABOLIC INHIBITORS ON RAT THYMOCYTES IN VITRO;Canadian Journal of Biochemistry and Physiology;1962-11-01

5. X-IRRADIATION OF RIBOSE AND DEOXYRIBOSE DERIVATIVES;Canadian Journal of Biochemistry and Physiology;1962-01-01

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