Author:
Kordová Nonna,Poffenroth Linda,Wilt John C.
Abstract
During the infection of L cells (clone 60 and 929) with egg-grown C. psittaci 6BC strain, lyosomes retained their integrity and L cells were not injured. Infected cells proliferated more intensely and showed higher mitotic indices from 24 h post infection than noninfected control cells. Chlamydial inclusions were released from the cytoplasm of infected L cells by pseudopodia-like extrusions. These events were in marked contrast to the effect of the L cell grown C. psittaci 6BC strain which caused activation of lysosomal acid phosphatase and damage of L cells. Previous comparative studies of the host lysosomal response to egg-grown as compared to cell culture grown C. psittaci 6BC strain in cultured macrophages and L cells are discussed.
Publisher
Canadian Science Publishing
Subject
Genetics,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Immunology,Microbiology
Cited by
16 articles.
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