Nanosilica A-300 influence on water structures formed on the bioactive agent Enoxil

Abstract

The interactions of water and aqueous solutions of HCl with the Enoxil preparation and its composite system Enoxil–SiO2 (1:1) have been studied by low-temperature 1H NMR spectroscopy. The antacid properties in the preparation, manifested in the transformation of a concentrated solution of HCl in a weakly concentrated one, have been established. In the composite system, adsorbed HCl in a hydrophobic environment of CDCl3 may generate a system of clusters with different acid concentrations, while the equilibrium is shifted toward less concentrated forms.