Isolation and characterization of a cytolysin produced by Vibrio cholerae serogroup non-O1-Reference-Cited by-同舟云学术

Isolation and characterization of a cytolysin produced by Vibrio cholerae serogroup non-O1

Published:1985-08-01 Issue:8 Volume:31 Page:711-720
ISSN:0008-4166
Container-title:Canadian Journal of Microbiology
language:en
Short-container-title:Can. J. Microbiol.

Author:

McCardell Barbara A.,Madden Joseph M.,Shah Dhirendra B.

Abstract

A thermolabile toxin (molecular weight, 52 711; isoelectric point, 8.65) produced by a clinical isolate of Vibrio cholerae serogroup non-O1 was cytotoxic for Y-1 mouse adrenal cells and Chinese hamster ovary cells. The toxin lysed rabbit red blood cells and produced a hemorrhagic zone in rabbit skin. When injected intravenously into adult mice, the cytolysin was rapidly lethal and caused fluid accumulation in both 5- and 18-h rabbit ileal loops. Strains of V. cholerae that produced cytolysin but no cholerae enterotoxin were able to cause fluid accumulation in rabbit intestinal loops.

Publisher

Canadian Science Publishing

Subject

Genetics,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Immunology,Microbiology

Link

http://www.nrcresearchpress.com/doi/pdf/10.1139/m85-135

Cited by 47 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. c-Jun Proto-Oncoprotein Plays a Protective Role in Lung Epithelial Cells Exposed to Staphylococcal α-Toxin;Frontiers in Cellular and Infection Microbiology;2018-05-25

2. Vibrio cholerae Cytolysin: Structure–Function Mechanism of an Atypical β-Barrel Pore-Forming Toxin;Advances in Experimental Medicine and Biology;2014-11-03

3. Non-O Group 1 Vibrio cholerae Strains Not Associated with Epidemic Disease;Vibrio cholerae and Cholera;2014-04-08

4. Toxins of Vibrio cholerae;Vibrio cholerae and Cholera;2014-04-08

5. The Famlily Vibrionaceae;The Prokaryotes;2014