Carbon-13 Nuclear Magnetic Resonance Spectra of 1,4-Oxathiane Derivatives

Abstract

The carbon-13 n.m.r. spectra of a series of 1,4-oxathianes, including the 4-oxide and 4,4-dioxide of 1,4-oxathiane, are reported. The results corroborated conclusions reached previously, on the basis of proton n.m.r. studies, concerning the conformational equilibria. The work also permitted a structural differentiation of the two nucleosides 6-chloro-9-(1,4-oxathian-2-yl)-9H-purine (1) and 6-chloro-9-(1,4-oxathian-3-yl)-9H-purine (2).