Author:
Kutney James P.,Tabata T.
Abstract
A synthetic sequence leading to 3,5-dimethyl-4-substituted pyridines is described. The sequence takes advantage of the steric influence exerted by substituents attached to the pyridine nucleus at the 3- and 5-positions on functional groups at the 4-position. In this manner a number of new trialkylated pyridines become available.
Publisher
Canadian Science Publishing
Subject
Organic Chemistry,General Chemistry,Catalysis
Cited by
7 articles.
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1. Wibaut-Arens Alkylation;Comprehensive Organic Name Reactions and Reagents;2010-09-15
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5. Convenient procedure for the synthesis of 2-monoalkylated indol-3-ones;Journal of the Chemical Society, Perkin Transactions 1;1991