THE EFFECT OF PYRIDOXINE DEFICIENCY ON BLOOD UREA IN MICE

Author:

Lyon Jr. John B.1,Arnold Eugene A.1,Farmer Rita1

Affiliation:

1. Department of Biochemistry, Division of Basic Health Sciences, Emory University, Emory University, Georgia

Abstract

Blood urea levels were determined in weanling, young, and adult C57 and I strain mice fed vitamin B6-deficient or complete rations. Elevations in blood urea were found in some of the deprived groups, but they were transient, and the maxima occurred early in the deficiency, at 2 weeks. Although the I strain is more susceptible to a B6 deficiency, strain differences were found in only one age group. Increases in blood urea were also induced by simple environmental changes. It was concluded that elevations in blood urea are not directly related to a pyridoxine deficiency in these inbred strains of mice.

Publisher

Canadian Science Publishing

Subject

General Medicine

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