Author:
Hullot Pierre,Cuvigny Thérèse,Larchevêque Marc,Normant Henri
Abstract
The α anions of N,N-disubstituted carboxamides can be conveniently prepared by treatment with "activated" lithium dialkylamides in HMPT. They react with aldehydes and ketones and lead to β-hydroxyamides; furthermore the ring opening of epoxides affords γ-hydroxyamides which may be cyclized in situ to γ-butyrolactones
Publisher
Canadian Science Publishing
Subject
Organic Chemistry,General Chemistry,Catalysis
Cited by
27 articles.
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