Author:
Orlowski Michael,Goldman Manuel
Abstract
The hypothesis that chlorpromazine inhibition of bacterial endospore germination acts at the level of hexose monophosphate shunt (HMP) dehydrogenases was tested and substantiated for Bacillus cereus T and Bacillus megaterium. However, this cannot be an exclusive mechanism of action in bacterial systems because inhibitory effects on growth and respiration are caused by the drug even when these HMP enzymes are not present in the organisms.
Publisher
Canadian Science Publishing
Subject
Genetics,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Immunology,Microbiology
Cited by
6 articles.
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