THE RELATION OF DIET, HORMONES, AND TUMORS TO THE ACTIVITY OF LIVER XANTHINE OXIDASE IN THE RAT
-
Published:1957-01-01
Issue:1
Volume:35
Page:881-887
-
ISSN:0576-5544
-
Container-title:Canadian Journal of Biochemistry and Physiology
-
language:en
-
Short-container-title:Can. J. Biochem. Physiol.
Author:
Burton A. F.1,
Begg R. W.1
Affiliation:
1. Collip Medical Research Laboratory, University of Western Ontario, London, Canada
Abstract
The activity of liver xanthine oxidase and of adenosine deaminase in rats was reduced to a low value when the animals were fed a low protein diet. This did not occur in tumor-bearing animals on the same diet. The maintenance of enzyme activity in the tumor-bearing animals could not be attributed to induced enzyme formation or to alteration in hormonal control, but may be associated with an increase in purine catabolism.
Publisher
Canadian Science Publishing