Glycemic and urinary volume responses in diabetic mellitus rats treated with Solanum lycocarpum

Author:

Farina Fabiane12,Piassi Flávia Grillo12,Moysés Margareth Ribeiro12,Bazzolli Denise Mara Soares12,Bissoli Nazaré de Souza12

Affiliation:

1. Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Av. Marechal Campos 1468, Vitória – ES – 29042-755, Brazil.

2. Faculdade Salesiana de Vitória, Vitória-ES, Brazil.

Abstract

Dietary fiber performs important functions in diabetes mellitus control and treatment. In this study, we evaluate the reduction in plasma glucose after the treatment of diabetic rats with high-fiber Solanum lycocarpum flour. We found that serum glucose, water and food intake, urine excretion, and urine sodium concentration were reduced in S. lycocarpum flour-treated diabetic rats (TDRs), compared with diabetic control rats (DCRs). In addition, TDRs did not show signs of kidney hypertrophy, unlike those in the DCR group. These results suggest that the use of S. lycocarpum flour can be an effective support in diabetes mellitus treatment.

Publisher

Canadian Science Publishing

Subject

Physiology (medical),Nutrition and Dietetics,Physiology,General Medicine,Endocrinology, Diabetes and Metabolism

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