Hydrolysis of Substituted Diphenylacetaldehyde Ethylene Glycol Cyclic Acetals in Aqueous Hydrochloric Acid

Abstract

The chemistry of DDT and DDD derivatives was explored by studying the steric and electronic effects on the hydrolysis of a variety of substituted diphenylacetaldehyde ethylene glycol cyclic acetals. This investigation demonstrated that ortho substituents, p-nitro, and p-methoxy groups affect the product distribution in different ways. The mechanistic details of this work are discussed.