Author:
Afong Michael,Olynyk Kimberley A.,Patel Hasmukh V.,Arnold John,Liao Shuen-Kuei,Freeman Karl B.
Abstract
The immunological relationship of the uncoupling protein from brown adipose tissue of several mammalian species was examined by using a rabbit antibody preparation against the rat protein. Complete cross-reactivity of the antibody to the protein from hamster, mouse, and rat was found, whereas the protein from rabbit cross-reacted only 25%. Cross-reactivity was also found with the human uncoupling protein, although the human protein was found to be about 1 kdalton smaller than the rat protein. No protein of the size of the uncoupling protein was detected in several tumor cell lines examined.
Publisher
Canadian Science Publishing
Cited by
12 articles.
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