Pathogenicity and Immunogenicity of Equine Herpesvirus Type 1 Mutants Defective in Either gI or gE Gene in Murine and Hamster Models

Author:

TSUJIMURA Koji1,YAMANAKA Takashi1,KONDO Takashi1,FUKUSHI Hideto2,MATSUMURA Tomio1

Affiliation:

1. Molecular Biology Division, Epizootic Research Center, Equine Research Institute, Japan Racing Association

2. Laboratory of Veterinary Microbiology, Faculty of Applied Biological Sciences, Gifu University

Publisher

Japanese Society of Veterinary Science

Subject

General Veterinary

Reference50 articles.

1. 1. Alber, D. G., Greensill, J., Killington, R. A. and Stokes, A. 1995. Role of T-cells, virus neutralizing antibodies and complement-mediated antibody lysis in the immune response against equine herpesvirus type-1 (EHV-1) infection of C3H (H-2k) and BALB/c (H-2d) mice. Res. Vet. Sci. 59: 205-213.

2. 2. Allen, G. P. and Bryans, J. T. 1986. Molecular epizootiology, pathogenesis, and prophylaxis of equine herpesvirus-1 infections. pp. 78-144. In: Progress in Veterinary Microbiology and Immunology, vol. 2 (Pandy, R. ed.), Karger, Basel.

3. 3. Allen, G. P., Kydd, J. H., Slater, J. D. and Smith, K. C. 1999. Advances in understanding of the pathogenesis, epidemiology and immunological control of equine herpesvirus abortion. pp. 129-146. In: Equine Infectious Diseases VIII (Wernery, U., Wade, J. F., Mumford, J. A. and Kaaden, O. R. eds.), R#38;W Publisher, Newmarket.

4. 4. Allen, G. P., Yeargan, M. R. and Bryans, J. T. 1983. Alterations in the equine herpesvirus 1 genome after in vitro and in vivo virus passage. Infect. Immun. 40: 436-439.

5. The Pathogenesis of Equine Herpesvirus Type 1 in the Mouse: A New Model for Studying Host Responses to the Infection

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