Effects of anemoside B4 on pharmacokinetics of florfenicol and mRNA expression of CXR, MDR1, CYP3A37 and UGT1E in broilers

Author:

LI Sicong12,LI Xuting12,YANG Rui12,WANG Bin12,LI Jinliang12,CAO Liang3,XIAO Songyang3,HUANG Wei3

Affiliation:

1. Institute of Veterinary Pharmacology, Sichuan Animal Science Academy, 7 Niusha Road, Jinjiang district, Chengdu 610066, PR China

2. Animal Breeding and Genetics Key Laboratory of Sichuan Province, 7 Niusha Road, Jinjiang district, Chengdu 610066, PR China

3. Sichuan Dingjian Animal Pharmaceutical Co., Ltd., 19 7th East Road, Checheng, Longquanyi district, Chengdu 610100, PR China

Publisher

Japanese Society of Veterinary Science

Subject

General Veterinary

Reference35 articles.

1. 1. Abd El-Aty, A. M., Goudah, A., Abo El-Sooud, K., El-Zorba, H. Y., Shimoda, M. and Zhou, H. H. 2004. Pharmacokinetics and bioavailability of florfenicol following intravenous, intramuscular and oral administrations in rabbits. Vet. Res. Commun. 28: 515–524.

2. 2. Balcomb, C. C., Angelos, J. A., Chigerwe, M., Byrne, B. A., Lane, V. M., Wetzlich, S. E., Sahin, O., Holler, L., Zhang, S. and Tell, L. A. 2018. Comparative pharmacokinetics of two florfenicol formulations following intramuscular and subcutaneous administration to sheep. Am. J. Vet. Res. 79: 107–114.

3. 3. Cannon, M., Harford, S. and Davies, J. 1990. A comparative study on the inhibitory actions of chloramphenicol, thiamphenicol and some fluorinated derivatives. J. Antimicrob. Chemother. 26: 307–317.

4. 4. Chen, M., Howe, D., Leduc, B., Kerr, S. and Williams, D. A. 2007. Identification and characterization of two chloramphenicol glucuronides from the in vitro glucuronidation of chloramphenicol in human liver microsomes. Xenobiotica 37: 954–971.

5. 5. Chinese Veterinary Pharmacopoeia Committee. 2015. Veterinary pharmacopoeia of the People’s Republic of China (2015 edition), China Agriculture Press, Beijing.

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