Effects of in vivo Administration of Anti-IL-10 or Anti-IFN-.GAMMA. Monoclonal Antibody on the Host Defense Mechanism against Plasmodium yoelii yoelii Infection.

Author:

KOBAYASHI Fumie1,ISHIDA Hiroshi2,MATSUI Toshihiro1,TSUJI Moriyasu1

Affiliation:

1. Department of Tropical Diseases and Parasitology, Kyorin University School of Medicine, Mitaka, Tokyo 181-8611, Japan

2. Department of Internal Medicine and Clinical Research Center, Utano National Hospital, Kyoto 616-8255, Japan

Publisher

Japanese Society of Veterinary Science

Subject

General Veterinary

Reference18 articles.

1. 1) Bienzle, U., Fritsch, K. G., Hoth, G., Rozdzinski, E., Kohler, K., Kalinowski, M., Kremsner, P., Rosenkaimer, F. and Feldmeier, H. 1988. Inhibition of Plasmodium vinckei-malaria in mice by recombinant murine interferon-γ. Acta. Trop. 45: 289-290.

2. Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.

3. 3) Clark, I. A., Hunt, N. H., Butcher, G. A. and Cowden, W. B. 1987. Inhibition of murine malaria (Plasmodium chabaudi) in vivo by recombinant interferon-γ or tumor necrosis factor, and its enhancement by butylated hydroxyanisole. J. Immunol. 139: 3493-3496.

4. 4) Favre, N., Ryffel, B., Bordmann, G. and Rudin, W. 1997. The course of Plasmodium chabaudi chabaudi infections in interferon-gamma receptor deficient mice. Parasit. Immunol.

5. 5) Green, L. C. D., Wagner, D. D. A., Glogowski, J., Skepper, P. L., Wishnok, J. S. and Tannenbaum, S. R. 1982. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Ann. Biohem. 126: 131-138.

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