Pretreatment of Macrophages with the Combination of IFN-.GAMMA. and IL-12 Induces Resistance to Leishmania major at the Early Phase of Infection-Reference-Cited by-同舟云学术

Pretreatment of Macrophages with the Combination of IFN-.GAMMA. and IL-12 Induces Resistance to Leishmania major at the Early Phase of Infection

Published:2008 Issue:6 Volume:70 Page:589-593
ISSN:0916-7250
Container-title:Journal of Veterinary Medical Science
language:en
Short-container-title:The Journal of Veterinary Medical Science

Author:

OTA Haruko¹,TAKASHIMA Yasuhiro²,MATSUMOTO Yoshitsugu³,HAYASHI Yoshihiro¹,MATSUMOTO Yasunobu¹

Affiliation:

1. Department of Global Animal Resource Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo

2. Department of Veterinary Parasitological Diseases, Faculty of Applied Biological Sciences, Gifu University

3. Department of Molecular Immunology, Graduate School of Agricultural and Life Sciences, The University of Tokyo

Publisher

Japanese Society of Veterinary Science

Subject

General Veterinary

Link

http://www.jstage.jst.go.jp/article/jvms/70/6/70_6_589/_pdf

Reference21 articles.

1. The role of mannose receptor during experimental leishmaniasis

2. Leishmania species: models of intracellular parasitism

3. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.

4. 4. Gazzinelli, R.T., Wysocka, M., Hayashi, S., Denkers, E.Y., Hieny, S., Caspar, P., Trinchieri, G. and Sher, A. 1994. Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii. J. Immunol. 153: 2533-2543.

5. 5. Green, S.J., Crawford, R.M., Hockmeyer, J.T., Meltzer, M.S. and Nacy, C.A. 1990. Leishmania major amastigotes initiate the L-arginine-dependent killing mechanism in IFN-γ-stimulated macrophages by induction of tumor necrosis factor-α. J. Immunol. 145: 4290-4297.

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