Age-dependent increase in activity of eukaryotic elongation factor 2 kinase in mesenteric arteries from spontaneously hypertensive rats
Author:
Affiliation:
1. Laboratory of Veterinary Pharmacology, School of Veterinary Medicine, Kitasato University, Higashi 23, Bancho 35-1, Towada, Aomori 034-8628, Japan
Publisher
Japanese Society of Veterinary Science
Subject
General Veterinary
Link
https://www.jstage.jst.go.jp/article/jvms/83/1/83_20-0564/_pdf
Reference15 articles.
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2. 2. Ashour, A. A., Gurbuz, N., Alpay, S. N., Abdel-Aziz, A. A. H., Mansour, A. M., Huo, L. and Ozpolat, B. 2014. Elongation factor-2 kinase regulates TG2/β1 integrin/Src/uPAR pathway and epithelial-mesenchymal transition mediating pancreatic cancer cells invasion. J. Cell. Mol. Med. 18: 2235–2251.
3. 3. Bannister, J. P., Bulley, S., Narayanan, D., Thomas-Gatewood, C., Luzny, P., Pachuau, J. and Jaggar, J. H. 2012. Transcriptional upregulation of α2δ-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension. Hypertension 60: 1006–1015.
4. 4. Carretero, O. A. and Oparil, S. 2000. Essential hypertension. Part I: definition and etiology. Circulation 101: 329–335.
5. 5. Fukuda, T., Kuroda, T., Kono, M., Miyamoto, T., Tanaka, M. and Matsui, T. 2014. Attenuation of L-type Ca2+ channel expression and vasomotor response in the aorta with age in both Wistar-Kyoto and spontaneously hypertensive rats. PLoS One 9: e88975.
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1. Eukaryotic elongation factor 2 kinase inhibitor, A484954 inhibits perivascular sympathetic nerve stimulation-induced vasoconstriction in isolated renal artery;European Journal of Pharmacology;2022-07
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