Substituted Amphetamines That Produce Long-Term Serotonin Depletion in Rat Brain (“Neurotoxicity”) Do Not Decrease Serotonin Transporter Protein Expression

Author:

ROTHMAN RICHARD B.,JAYANTHI SUBRAMANIAM,CADET JEAN L.,WANG XIAOYING,DERSCH CHRISTINA M.,BAUMANN MICHAEL H.

Publisher

Wiley

Subject

History and Philosophy of Science,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Reference24 articles.

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2. Brain serotonin neurotoxicity and primary pulmonary hypertension from fenfluramine and dexfenfluramine;McCann;A systematic review of the literature. JAMA,1997

3. Effects of repeated fenfluramine administration on indices of monoamine function in rat brain: pharmacokinetic, dose response, regional specificity and time course data;Zaczek;J. Pharmacol. Exp. Ther,1990

4. Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse;O'Callaghan;J. Pharmacol. Exp. Ther,1994

5. Loss of serotonin uptake sites and immunoreactivity in rat cortex after dexfenfluramine occur without parallel glial cell reactions;Rowland;Brain Res,1993

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