Cell Viability Score as an Integrated Indicator for Cytotoxicity of Benzalkonium Chloride-Containing Antiglaucoma Eyedrops

Author:

AYAKI MASAHIKO,IWASAWA ATSUO,NIWANO YOSHIMI

Publisher

The Society for Antibacterial and Antifungal Agents, Japan

Subject

Public Health, Environmental and Occupational Health,Applied Microbiology and Biotechnology

Reference28 articles.

1. Ammar, D. A., Noecker, R. J., and Kahook, M.Y. (2011) Effects of benzalkonium chloride- and polyquad-preserved combination glaucoma medications on cultured human ocular surface cells. Adv. Ther., 28, 501-510.

2. Asada, H., Takaoka-Shichijo, Y., Nakamura, M., and Kimura, A. (2010) Optimization of benzalkonium chloride concentration in 0.0015% tafluprost ophthalmic solution from the points of ocular surface safety and preservative efficacy. Yakugaku Zasshi, 130, 867-871. in Japanese.

3. Ayaki, M., and Iwasawa, A. (2010) . Cytotoxicity of prostaglandin analog eye drops preserved with benzalkonium chloride in multiple corneoconjunctival cell lines. Clin. Ophthalmol., 4, 919-924.

4. Ayaki, M., and Iwasawa, A. (2011b) Critical concentration of benzalkonium chloride in eye drop for toxicity in cultured ocular surface cell lines. Inv. Ophthalmol. Vis. Sci., 52, E-Abstract 1955.

5. Ayaki, M, Yaguchi, S, Iwasawa, A,, and Koide, R. (2011c) Cytotoxicity of six ophthalmic solutions containing carteolol for four cultured corneal and conjunctival cell lines. Folia Japonica de Ophthalmologica Clinica. (in Japanese) , 4, 348-354.

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