Reconstruction of a skull base defect with cutaneous nasocranial communication using a combination of an anterolateral thigh free flap and galeal flap division: a case report

Abstract

Soft tissue defects can occur in the head and neck due to various causes, and head and neck surgery is often performed to reconstruct soft tissue defects. However, head and neck reconstruction remains delicate and complex as a surgical procedure. The reconstruction of a large defect at the base of the skull, especially after resection of cancer in the anterior base of the skull that has invaded adjacent tissues, is particularly difficult. We present a case of successful reconstruction of a large skull base defect using an anterolateral thigh (ALT) free flap and galeal flap division after tumor resection in the anterior skull base. Paranasal sinus cancer involving the bilateral frontoethmoidal sinuses was resected, and an anterior skull base defect was noted, with communication between the intracranium and nasal cavity and a skin defect at the glabella. A galeal flap was divided to create an anatomical and functional barrier to communication between the nasal cavity and intracranium. The soft tissue defect at the anterior skull base was then reconstructed using an ALT free flap containing the vastus lateralis muscle, and the skin defect at the glabella was covered. No postoperative complications, such as cerebrospinal fluid leakage, developed. The reconstructed flap remained intact after subsequent radiation therapy. Based on this study, we propose that using a galeal flap and ALT free flap in a large skull base defect can yield a robust flap that can endure postoperative radiotherapy with a minimal risk of complications.